Thank you for sending us your paper “Downregulation of HlpxE-mediated transcription doubles median life-span expectancy in humans”, but I am afraid we cannot offer to publish it in The Current Biologist.
We appreciate the interest in the issue you are addressing, and your results sound potentially significant for the field, but our feeling is that at this stage your paper would be better suited to a somewhat more specialised journal.
I am sorry that we cannot give you a more positive response, but thank you for your interest in The Current Biologist.
Many of us —professional scientists writing research articles— have had to confront this type of letters from journal editors. We have grown accustomed to them. A standard cut-and-paste piece of text used knee-jerkedly by editors without much thought or consideration. We file them promptly, and move on. After all, there are plenty of journals around, both general and specialized. No big deal, right?
However, the concept of “a more specialized journal” remains as elusive as ever. Admitedly, The Current Biologist is a half-invented journal, but there are still plenty like it that claim to be “generalists” and yet publish papers with titles like “Slicing-Independent RISC Activation Requires the Argonaute PAZ Domain” or “Distinct Roles of Talin and Kindlin in Regulating Integrin α5β1 Function and Trafficking” or “SUMOylation of the α-Kleisin Subunit of Cohesin Is Required for DNA Damage-Induced Cohesion“ and so forth… How about that for “specialized” knowledge?
A journal that publishes papers containing three or more abbreviations or jargon terms in their titles can not honestly claim to be a generalist. To ask their authors to submit their work to a more specialized journal is –at the very least– disrespectful to the authors who have put so much work behind a research study. Understandably, however, polite alternatives require more time and effort from journal editors. “We feel that the results presented in your manuscript lack mechanistic insights and therefore seem too preliminary for our journal” would seem like a more honest and realistic alternative. Or why not simply let them know the truth: “The topic of your study falls outside the scope of our journal”? Alas, either of these requires editors to have read the manuscript, which —sadly— is not always the case.
Perhaps it’s time to launch the “Journal of Specialized Biology” , a forum for all those research papers that —like the one above on human life-span doubling— have been deemed to too specialized for die-hard “Argonaute PAZ Domain” generalists.