Open access journals charge fees to their authors for publication of accepted articles. Some of those fees can be quite significant. Cell Reports, a new journal from Cell Press, charges $5,000 per article, the highest among open access research periodicals. There is currently a debate as to whether the journals that charge the most are the most influential. A recent survey appears to indicate that price doesn’t always buy prestige in open access. My friend and colleague M.F. has recently made a prescient comment in this context: “…but apart from the commercial desire to maximize profits, the pricing is probably designed as part of the brand signal, to make the point that this should be in the very top tier of journals. Similar to launching a new “premium” wine to the market, if price on release is low, the consumers will never perceive it as a premium wine… . Time will tell if this self-fulfilling prophecy is indeed true, or if journals like Open Biology or eLife can completely break that model.“